該基因編碼細胞色素p450酶超家族的一個成員。細胞色素p450蛋白是一種單加氧酶，催化藥物代謝和膽固醇、類固醇等脂類的合成。該基因編碼的酶定位于內質網，代謝前致癌物，如多環芳烴和17β-雌二醇。這種基因的突變與原發性先天性青光眼有關，因此人們認為這種酶也代謝了一種參與眼睛發育的信號分子，可能是類固醇。[由RefSeq提供，2008年7月]
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008]
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