該基因編碼的蛋白質與阿托品-1相互作用。阿托品-1含有一個多聚谷氨酸重復序列，其擴增導致齒齦和蒼白球萎縮。該編碼蛋白具有兩個ww結構域，一個鳥苷酸激酶樣結構域和多個pdz結構域。其結構與膜相關鳥苷酸激酶同源物（maguk）家族相似。[由RefSeq提供，2008年7月]
The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008]