這個基因編碼一個小GTP酶的rho家族成員，在非活性GDP結合態和活性GTP結合態之間循環，在信號轉導級聯中起分子開關的作用。rho蛋白促進肌動蛋白細胞骨架的重組并調節細胞的形狀、附著和運動。該基因的過度表達與腫瘤細胞增殖和轉移有關。已識別出多個可選拼接變體。
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.