這個基因編碼腫瘤壞死因子受體超家族的一個成員。編碼蛋白在激活炎癥和抑制t細胞免疫反應的信號轉導途徑中發揮作用。它與單純皰疹病毒（hsv）包膜糖蛋白d（gd）結合，介導其進入細胞。選擇性剪接導致多個轉錄變體。[由RefSeq提供，2014年7月]
This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]