ABSCIEX與美CDC合作改善臨床研究

共同努力使LC/MS在臨床實驗室對于類固醇激素測試更加便利

　　福斯特市，加利福尼亞，AB SCIEX，生命科學分析技術的全球領導者，近日宣布與美疾病控制與預防中心（CDC）合作，并創立CDC基金會來支持質譜技術在臨床實驗室中激素檢測的運用。這一合作的目的在于幫助支持CDC的激素標準化項目，從而提高實驗室結果的可靠性，幫助評估疾病風險并監控治療。

　　建立激素標準化項目的目標是應對臨床研究中現階段面臨的挑戰，這些挑戰包括：在研究和測量系統中缺少數據的可比性；缺乏尤其是在低濃度范圍內缺乏適當的檢測性能，比如在婦女和兒童體內觀測到的睪丸激素級。為了推進這一項目，CDC正在開發一個參考方法，該方法用質譜來提高結果的可比性、特異性和可靠性，并幫助實現更加準確的測試。

　　質譜是一種先進的科學儀器，基于分子組成的不同來分析化合物。質譜能夠掃描、鑒定和定量測定各種分子，包括擴睪丸激素和其它激素。CDC的參考方法使用的是液相色譜-質譜聯用方法（LC/MS）。AB SCIEX通過貢獻CDC基金的方式向CDC提供了AB SCIEX QTRAP^? 5500系統。QTRAP系統是獲獎的質譜產品，是整體解決方案中的一部分，整體解決方案還包括用于臨床研究的“可立快”（Cliquid^?） 軟件，這是一款自動化的應用軟件，用于簡化質譜在臨床研究中的流程。

AB SCIEX QTRAP 5500質譜儀

可立快Cliquid軟件

　　本網站收錄相關儀器：

　　QTRAP5500 四極桿-線性阱雜交質譜儀

　　Joe Anacleto, AB SCIEX公司副總裁兼應用市場和臨床研究事業部經理說：“AB SCIEX盡其所能地通過擴展質譜的應用來幫助提升臨床研究的水平。我們十分珍惜這次與CDC合作的機會，幫助CDC不斷提高激素測定結果的準確性。AB SCIEX臨床研究解決方案為這一重要分析提供了一流的領先技術。”

　　關于AB SCIEX

　　AB SCIEX是生命科學分析技術開發領域的全球領先企業，幫助科學家應對復雜的科學挑戰。公司提供科學儀器、軟件和服務，用于發現新藥、促進醫學科學發展、保護食品供應鏈和環境。AB SCIEX的技術解決方案結合了最高的性能和最高的穩定性，確保我們的用戶進行科學發現、可靠地傳遞結果和提高生命質量。AB SCIEX擁有近30年的創新歷史，在市場中一直出于領先地位，其前身為美國應用生物系統公司（Applied Biosystems）和美迪希（MDS）實驗儀器公司的合資企業。2010年1月30 日，AB SCIEX作為丹納赫集團的子公司開始運營。更多資料請訪問官網：www.absciex.com。

　　參考英文：

AB SCIEX Collaborates with the Centers for Disease Control and Prevention to Improve Clinical Research

　　Joint efforts to facilitate the use of LC/MS in clinical laboratories for steroid hormone testing

　　FOSTER CITY, Calif. – AB SCIEX, a global leader in life science analytical technologies, announced a collaboration with the Centers for Disease Control and Prevention (CDC) and the CDC Foundation to facilitate the use of mass spectrometry technologies in clinical laboratories for hormone testing. This collaboration is intended to help support the CDC's Hormone Standardization Project for improving the reliability of laboratory results used to help assess disease risk and monitor treatment.

　　The Hormone Standardization Project aims to address current challenges in clinical research, including lack of comparability of data across studies and measurement systems as well as lack of appropriate performance of assays, especially at low concentrations, such as testosterone levels observed in women and children. To advance this project, the CDC is working to develop a reference method using mass spectrometry to improve comparability, specificity, and reliability of results and help facilitate more accurate testing practices.

　　Mass spectrometry is an advanced scientific technique used to analyze compounds based on their molecular composition. Mass spectrometers scan, identify, and measure the quantity of various molecules, including testosterone and other hormones. The CDC's reference method utilizes mass spectrometry combined with high-performance liquid chromatography (LC/MS). AB SCIEX provided the CDC with the use of an AB SCIEX QTRAP? 5500 System through a contribution to the CDC Foundation. The QTRAP system is an award-winning mass spectrometer that is part of an integrated solution, which also features Cliquid? Software for Clinical Research, an automated software application designed to simplify the use of mass spectrometry for clinical researchers.

　　Joe Anacleto, Vice President and General Manager of the Applied Markets and Clinical Research Business, AB SCIEX

　　 “AB SCIEX is well-positioned to help advance clinical research through the expanded use of mass spectrometry. We value the opportunity to assist the CDC in advancing improved accuracy of results for hormone testing. AB SCIEX clinical research solutions use best-in-class technology for this critical analysis.”

　　About AB SCIEX

　　AB SCIEX is a global leader in the development of life science analytical technologies that help answer complex scientific challenges. The company provides scientific instrumentation, software and services used to discover new drugs, advance medical science and protect the food supply and the environment. AB SCIEX technology solutions combine the highest performance with the highest reliability to enable our customers to fuel scientific discovery, deliver results with confidence and improve the quality of life. The company has a more than 20-year history of innovation and market leadership as the former Applied Biosystems/MDS Analytical Technologies joint venture. For more information about AB SCIEX, go to www.absciex.com. Follow AB SCIEX on Twitter @ABSCIEX and on Facebook.

　　Social Media Tags

　　AB SCIEX, mass spectrometry, CDC, testosterone, hormone testing, QTRAP, clinical research, Hormone Standardization Project