該基因編碼一個富含AT的相互作用域（ARID）的DNA結合蛋白家族成員。 ARID家族的成員在胚胎模式，細胞譜系基因調控，細胞周期控制，轉錄調控和染色質結構修飾中發揮作用。 該蛋白作為多溴和BRG1相關因子或PBAF（SWI / SNF-B）染色質重塑復合物的亞基，通過核受體促進配體依賴性轉錄激活。 該基因的突變與肝細胞癌有關。 該基因的假基因位于第1號染色體上。 [由RefSeq提供，2016年12月]
This gene encodes a member of the AT-rich interactive domain (ARID)-containing family of DNA-binding proteins. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and chromatin structure modification. This protein functions as a subunit of the polybromo- and BRG1-associated factor or PBAF (SWI/SNF-B) chromatin remodeling complex which facilitates ligand-dependent transcriptional activation by nuclear receptors. Mutations in this gene are associated with hepatocellular carcinomas. A pseudogene of this gene is found on chromosome1. [provided by RefSeq, Dec 2016]