Prenyl轉移酶可通過C-末端Caax盒將硫醚連接的法尼酰基或香葉基與蛋白質的半胱氨酸殘基結合。caax-geranylgeranyltransferase和caax-farnesyltransfer是具有相同α亞基但具有不同β亞基的異二聚體。這個基因編碼這些轉移酶的α亞單位。選擇性剪接導致多個轉錄變體相關假基因已在11號和13號染色體上鑒定。[由RefSeq提供,2010年5月]
Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010]