該基因編碼胞質蛋白酪氨酸激酶，參與鈣誘導的離子通道調節和MAP激酶信號通路的激活。編碼蛋白可能是神經肽激活受體或增加鈣通量的神經遞質與調節神經元活性的下游信號之間的一個重要信號中間產物。編碼蛋白在細胞內鈣濃度增加、煙堿乙酰膽堿受體活化、膜去極化或蛋白激酶C活化的作用下迅速進行酪氨酸磷酸化和活化。這種蛋白已被證明能結合CRK相關底物、腎囊腫蛋白、與FAK相關的GTPase調節因子和GRB2的SH2結構域。編碼蛋白是蛋白酪氨酸激酶fak亞家族的成員，但與其他亞家族的激酶缺乏顯著的序列相似性。四個轉錄變異體編碼兩種不同的亞型已被發現這個基因。
This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.