該基因的產物是一種絲裂原誘導的gtpase激活蛋白（gap）。它對ras相關的調節蛋白rap1和rap2表現出特異的gap活性，但對ran或其他小gtpase則沒有。當異常或過早表達時，這種蛋白也可能阻礙有絲分裂原誘導的細胞周期進程。它局限于核周區迄今為止，已經對編碼相同亞型的兩個交替拼接變體進行了表征。[由RefSeq提供，2008年7月]
The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 2008]