該基因編碼一種生長抑制蛋白，被認為在穩定塊莖素中起作用。這種基因的突變與結節性硬化癥有關。選擇性剪接導致多個轉錄變體。
This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.