短/支鏈酰基輔酶a脫氫酶(ACADSB)是脂肪酸或支鏈氨基酸代謝中催化酰基輔酶a衍生物脫氫的酶家族中的一員底物特異性是定義該基因家族成員的主要特征。acadsb基因產物對短支鏈酰基輔酶a衍生物(s)-2-甲基丁基輔酶a具有最大的活性,但也與其他2-甲基支鏈底物和短直鏈酰基輔酶a發生顯著反應。該cDNA編碼線粒體前體蛋白,該蛋白在線粒體導入時被裂解,并預測產生約43.7 kDa的成熟肽。[由RefSeq提供,2008年7月]
Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-KDa. [provided by RefSeq, Jul 2008]