WIKI資訊
Cyclins are proteins that associate with cyclin-dependent protein kinases to regulate their activity and the progression of the cell cycle through specific checkpoints. Disruption of cyclin action can lead to either cell cycle arrest, or to uncontrolled cell cycle proliferation. The cyclical increase and decrease in cyclin levels is a key to cell cycle regulation. When cyclin E is abundant it interacts with the cell ......閱讀全文
E2F-1 is a transcription factor that regulates the expression of genes involved in the cell cycle and that is involved in progression of the cell cycl