Interleukin6InducedAcutePhenotypicMicroenvironmentPromote...（五）
Figure 2. Proteomics analysis of serum glycoproteins from treated and untreated mice. 21 days after cell injection, mice underwent cryo-thermal or no treatment as control. Afterwards, mice were kept for another 2 h, 2, 5, 8, 11, 14, 21 and 28 days. For shotgun proteomics, serum were collected and pooled under each condition. After protein denaturation, reduction and alkylation, pooled sera were ......閱讀全文
Interleukin-6 Induced Acute Phenotypic Microenvironment Promote...（五）
??Figure 2. Proteomics analysis of serum glycoproteins from treated and untreated mice. 21 days after cell injection, mice underwent cryo-thermal or
Interleukin-6 Induced Acute Phenotypic Microenvironment Promote...（三）
? Target analysis by Parallel reaction monitoring (PRM) The targeted quantification and verification were carried out in 94 serum samples with 5~
Interleukin-6 Induced Acute Phenotypic Microenvironment Promote...（四）
Flow cytometry Spleens were extracted after therapy and mechanically homogenized with gentle MACS Dissociator to obtain a single-cell splenocyte
Interleukin-6 Induced Acute Phenotypic Microenvironment Promote...（八）
In summary, we suggested that “acute” response could elicit innate and Th1 adaptive immunity, reversing the tumor-mediated immunosuppressive envi
Interleukin-6 Induced Acute Phenotypic Microenvironment Promote...（十）
In this study, we found that “acute” response was strongly induced by cryo-thermal therapy with “acute” and high expression of a series of acute
Interleukin-6 Induced Acute Phenotypic Microenvironment Promote...（二）
As a primary component of circulatory system, serum is the major reservoir of thousands of proteins secreted or “leaked” from a broad spectrum of
Interleukin-6 Induced Acute Phenotypic Microenvironment Promote...（七）
Figure 7. The expression of three acute phase proteins after IL-6 neutralization. Mice were injected intraperitoneally with mouse anti-IL-6 Ab 3 and
Interleukin-6 Induced Acute Phenotypic Microenvironment Promote...（六）
Cryo-thermal therapy induced an “acute” phase response?First, we performed PRM analysis upon significant proteins involved in acute phase response,
Interleukin-6 Induced Acute Phenotypic Microenvironment Promote...（一）
Interleukin-6 Induced Acute Phenotypic Microenvironment Promotes Th1 Anti-Tumor ImmunityTing Xue1, Ping Liu1, Yong Zhou2, Kun Liu1, Li Yang2, Robert L
Interleukin-6 Induced Acute Phenotypic Microenvironment Promote...（九）
The strongest and unique “acute” environment induced by cryo-thermal therapy stimulated the most effective anti-tumor immune response?As described