MicroarraystoCharacterizetheMolecularGeneticBasisofDisease
article by Dr. RL McInnes, Agilent Technologies, AustraliaGenomic instability underlies cancer and Copy Number Aberrations (CNA s) are known to underpin many developmental disorders. Combined with microarray-based tools to interrogate changes in gene expression, promoter occupancy, chromatin modifications and DNA methylation, researchers can now very thoroughly characterize the molecular-genetic basis of dise......閱讀全文
Microarrays to Characterize the Molecular-Genetic Basis of Disease
article by Dr. RL McInnes, Agilent Technologies, AustraliaGenomic instability underlies cancer and Copy Number Aberrations (CNA s) are known to underp
PAM: Prediction Analysis for Microarrays
PAM: Prediction Analysis for MicroarraysClass Prediction and Survival Analysis for Genomic Expression Data Mining?Features:Performs sample classificat
Inhibition of Huntington's disease neurodegeneration
Huntington's disease is a neurodegenerative condition caused by a dominant mutation in a gene encoding a protein now called huntingtin. Large poly
Deregulation of CDK5 in Alzheimers Disease
Cyclin-dependent kinase 5 (cdk5), a multi-functional kinase, and its neuron-specific activator p35 are required for neurite outgrowth and cortical lam
Alpha-synuclein and Parkin-mediated proteolysis in Parkinson's disease
The motor defects of Parkinson's disease are related to the loss of dopaminergic neurons in specific brain regions. Examination of these neurons i
第一屆Cell Death and Disease研討會會議通知
第一屆Cell Death and Disease研討會暨第四屆中英“細胞死亡、干細胞與癌癥”國際研討會將于2013年5月8日~9日在上海召開。 本次會議主題為：細胞死亡、干細胞與免疫，將邀請海內外相關領域卓有建樹的科學家，采用大會報告及專題討論的形式，結合國際上癌癥生物學研究領域的前
Cell Death & Disease免疫、干細胞與疾病 國際研討會召開
10月12日至14日，第五屆Cell Death & Disease免疫、干細胞與疾病國際研討會在中國常州市明都真儒酒店會議廳召開。常州市副市長張云云、衛生局黨委書記、局長王莉、常州市第一人民醫院院長何小舟、中國科學院上海生命科學研究院健康科學研究所主持工作的副所長孔祥銀等領導出席會議開幕式并講
BBA-Mol Basis Dis：omega-6脂肪酸可以幫助對抗心臟病
卡迪夫大學的研究人員與本-古里安大學合作進行的一項新研究發現，omega-6多不飽和脂肪酸可能有助于對抗心臟病。這項名為"Dihomo-gamma-linolenic acid inhibits several key cellular processes associated with ath
單項血脂和血脂比值與冠狀動脈病變嚴重程度的相關性
? Correlation of individual blood lipid and blood lipid ratio with severity of coronary artery disease ABSTRACT: Objective? To probe into the corre
DISEASE In A DISH | 基于誘導多功能干細胞iPSC來源的藥物研發
山中伸彌(Shinya Yamanaka)，京都大學iPS細胞研究所所長，因在“誘導多功能干細胞(induced Pluripotent Stem Cell, iPSC)”的卓越貢獻，被授予2012年諾貝爾生理或醫學獎[1]。?“iPSC來源于病人體細胞，有望為重大疾病的新藥開發提供強有力的治療工具