ABSCIEX和ARUP實驗室聯合開發激素分析臨床研究新方法

　　2011年2月7日——全球生命科學分析技術的領導者AB SCIEX 公司，今天宣布與美國主要的臨床基準實驗室ARUP 實驗室合作，共同開發新的測試方法供全球實驗室采用，從而提高對激素的分析水平，在使用了AB SCIEX的QTRAP^? 5500質譜技術后，ARUP的研究人員得到了以前臨床研究中無法獲得的結果。這一進展有望獲得更好的結果，用以提高醫療保健的水平。2001年2月初，在圣地亞哥舉辦的臨床實驗室質譜應用研討會（Mass Spectrometry Applications for the Clinical Laboratory (MSACL) conference）上，AB SCIEX公司展示了其QTRAP^? 技術。

QTrap 5500質譜儀

　　與領先的臨床基準實驗室合作旨在推進全行業逐漸使用質譜儀器來進行激素分析。因為很多激素的存在豐度極低，免疫測試方法往往被干擾所困，無法獲得精確的測量結果。為應對這一挑戰，ARUP轉向使用QTRAP^? 技術獲得更高水平的靈敏度——這一點在低豐度激素的精確定量中很有必要，尤其對于游離激素；同時，用Qtrap同一臺儀器的定性能力來進行結果的驗證也很重要。

　　在基于質譜的臨床研究中，AB SCIEX 公司提供當今市場上最高靈敏度的儀器，并提供一個簡單的、四步法的工作流程。在一個平臺上，AB SCIEX QTRAP^? 5500 系統集高靈敏度、高速度于一身；集成了定性和定量分析能力，代表著更高類型的三重四極桿儀器。在同AB SCIEX科研人員的合作中，ARUP的研究人員用QTRAP^? 技術開發了新的測試方法，AB SCIEX公司計劃把這一方法轉變成預先配置的iMethod? 測試方法，使之能夠易于下載到AB SCIEX Cliquid^? 軟件中。在臨床研究中，可立快Cliquid^? 軟件可顯著簡化高端質譜技術的操作，讓使用更方便。

　　Alan Rockwood博士，ARUP 實驗室質譜室的科學主管

　　“在ARUP的質譜實驗室中，我們的任務就是獲得盡可能低的定量分析的檢出限，這樣我們才能為臨床研究提供更好的結果。在合作中，AB SCIEX的科學家們花時間來了解我們苛刻的要求，使我們更好地應用質譜技術來完成我們的目標。通過提供比從前更準確的答案，我們正在努力為提高醫療服務提供支持。”

　　Joe Anacleto, AB SCIEX應用市場和臨床研究業務部副總裁兼總經理

　　“向基于質譜的臨床研究轉變還將加速。像ARUP這樣領先的臨床基準實驗室，使用QTRAP^? 技術進行方法開發，使AB SCIEX技術提供的高靈敏度變得更主要。通過成為臨床研究者值得信賴的合作伙伴，AB SCIEX能夠令實驗室更輕松地使用質譜、并獲得更好的結果。”

　　關于AB SCIEX

　　AB SCIEX是生命科學分析技術開發領域的全球領先企業，幫助科學家應對復雜的科學挑戰。公司提供科學儀器、軟件和服務，用于發現新藥、促進醫學科學發展、 保護食品供應鏈和環境。AB SCIEX的技術解決方案結合了最高的性能和最高的穩定性，確保我們的用戶進行科學發現、可靠地傳遞結果和提高生命質量。AB SCIEX擁有近超過20年的創新歷史，在市場中一直出于領先地位，其前身為美國應用生物系統公司（Applied Biosystems）和美迪希（MDS）實驗儀器公司的合資企業。更多資料請訪問官網：www.absciex.com。

　　本網收錄相關儀器：QTRAP5500 四極桿-線性阱雜交質譜儀

      參考英文原文　　

AB SCIEX and ARUP Laboratories Collaborate to Develop New Clinical Research Methods for Hormone Analysis

　　AB SCIEX, a global leader in life science analytical technologies, today announced a collaboration with ARUP Laboratories, a major clinical reference laboratory in the United States, to develop new test methods that clinical research laboratories around the world can adopt to improve hormone analysis. ARUP researchers are using AB SCIEX QTRAP^? 5500 mass spectrometry technology to obtain results that were previously unavailable to clinical researchers. This advancement is expected to help deliver better answers that can be used to improve healthcare. AB SCIEX is exhibiting QTRAP^? technology at Mass Spectrometry Applications for the Clinical Laboratory (MSACL) conference in San Diego this week.

　　This collaboration with a leading clinical reference laboratory is intended to help drive the industry-wide move toward increasingly using mass spectrometry to conduct hormone analysis. Because many hormones exist in extremely low abundance, immunoassay-based approaches are often plagued by interferences, preventing them from obtaining accurate measurements. To address this challenge, ARUP turned to QTRAP^? technology to obtain a higher level of sensitivity, which is needed to perform the most accurate quantitation of low abundant hormones, especially free hormones, while confirming the results with qualitative capabilities within the same system.

　　AB SCIEX provides the highest sensitivity instrumentation on the market today as part of a simple, four-step workflow for mass spectrometry-based clinical research. The AB SCIEX QTRAP^? 5500 System combines high sensitivity and speed on a platform that integrates quantitative and qualitative analysis, representing a better type of triple quadrupole. In collaboration with AB SCIEX scientists, ARUP researchers are using this technology to develop new test methods that AB SCIEX plans to turn into pre-configured iMethod? Tests available for easy download into AB SCIEX Cliquid^? Software, which is a software application that significantly simplifies the use of advanced mass spectrometry technology for clinical research.

　　Alan Rockwood, Ph.D., Scientific Director of the Mass Spectrometry Lab at ARUP Laboratories

　　“Our mission in the mass spectrometry lab of ARUP is to push the limits of quantitation as low as we can, so we can deliver better results for clinical research. Our collaboration with AB SCIEX, whose scientists have taken the time to understand our stringent requirements, gives us access to mass spectrometry technology that helps us to fulfill our purpose. By providing more accurate answers than previously possible, we are supporting efforts to improve medical care.”

　　Joe Anacleto, Vice President and General Manager of the Applied Markets and Clinical Research Business, AB SCIEX

　　“The shift to mass spectrometry-based clinical research continues to rapidly accelerate. To have a leading clinical reference laboratory such as ARUP Laboratories utilize QTRAP^? technology for method development reinforces the importance of high sensitivity that AB SCIEX technology delivers. By being a trusted partner with clinical researchers, AB SCIEX is able to make it easier for laboratories to adopt mass spectrometry and obtain better answers.”

　　About AB SCIEX

　　AB SCIEX is a global leader in the development of life science analytical technologies that help answer complex scientific challenges. The company provides scientific instrumentation, software and services used to discover new drugs, advance medical science and protect the food supply and the environment. AB SCIEX technology solutions combine the highest performance with the highest reliability to enable our customers to fuel scientific discovery, deliver results with confidence and improve the quality of life. The company has a more than 20-year history of innovation and market leadership as the former Applied Biosystems/MDS Analytical Technologies joint venture. For more information about AB SCIEX, go to www.absciex.com.

　　英文原文鏈接：AB SCIEX and ARUP Laboratories Collaborate to Develop New Clinical Research Methods for Hormone Analysis