WIKI資訊
Significant progress has been made towards delineation of the intrinsic molecular processes that regulate B lymphocyte immune function. Recent observations have provided a clearer picture of the interactive signaling pathways that emanate from the mature B cell antigen receptor (BCR) complex and the different precursor complexes that are expressed during development. Studies have also revealed that the net functional......閱讀全文
RT2 PCR Profiler Arrays可用于生物學和醫學研究的各個領域，包括：癌癥研究、炎癥和細胞因子分析、干細胞研究、神經生物學、信號轉導通路研究、細胞黏附和細胞遷移、生物標記分子篩選和驗證截止目前，QIAGEN 擁有專利申請的PCR Ar
Sonic Hedgehog (Shh) is one of a family of three secreted proteins, including Indian Hedgehog (Ihh) and Desert Hedgehog (Dhh), that play distinct and
Four different members of the Sprouty protein family block the cellular proliferation and differentiation induced by several different growth factors,
Axons extend significant distances to innervate target tissues. At the site of innervation, target tissues release neurotrophins including NGF, BDNF a
ObjectiveThis experiment attempted to determine the effects of the teratogen cyclopamine on the Shh signaling pathway in axolotl embryos. Groups of ax
Sonic Hedgehog (Shh) is a secreted protein identified genetically as an important developmental factor. Shh provides a morphogenic signal in the devel
The role of Hemophilus influenzae in ear infections and chronic obstructive pulmonary disease includes the induction of an inflammatory response throu
IL-10 is a cytokine with potent anti-inflammatory properties, repressing the expression of inflammatory cytokines such as TNF-alpha, IL-6 and IL-1 by
lncRNA研究是目前生命科學領域的研究熱點，但是，目前對于lncRNA的功能理解還處于初級階段。據不完全統計，目前已知功能的lncRNA不超過1000條。因此，怎么在現有基礎上去挖掘lncRNA的生物學功能呢？針對lncRNA和mRNA的共表達研究，為我們理解lncRNA在疾病中的生物學功能提供了
lncRNA研究是目前生命科學領域的研究熱點，但是，目前對于lncRNA的功能理解還處于初級階段。據不完全統計，目前已知功能的lncRNA不超過1000條。因此，怎么在現有基礎上去挖掘lncRNA的生物學功能呢？針對lncRNA和mRNA的共表達研究，為我們理解lncRNA在疾病中的生物學功能提
lncRNA研究是目前生命科學領域的研究熱點，但是，目前對于lncRNA的功能理解還處于初級階段。據不完全統計，目前已知功能的lncRNA不超過1000條。因此，怎么在現有基礎上去挖掘lncRNA的生物學功能呢？針對lncRNA和mRNA的共表達研究，為我們理解lncRNA在疾病中的生物學功能提
Helper T cells are found in two distinct cell types, Th1 and Th2, distinguished by the cytokines they produce and respond to and the immune responses
Skeletal muscle atrophies with disuse while with increased use and increased load skeletal muscle exhibits hypertrophy, with an increase in the size o
Signaling by interferon-gamma stimulates anti-viral responses and tumor suppression through the heterodimeric interferon-gamma receptor. Signaling is
Hippo信號通路是近年來在果蠅中研究發現的一個高度保守的生長控制信號通路，其對器官大小及細胞增殖和凋亡都具有關鍵的調節作用。該通路由多種抑癌基因及一種候選癌基因組成，此通路的失活或者異常表達在動物實驗中參與多種疾病的發生。 &
在免疫學實驗中，比如WB，IHC，IF等，大家都知道選著好正確的一抗，往往實驗就成功了一大半，因此，往往很多研究者便會忽視對二抗，以及其它試劑盒品質的追求。二抗是一種相對而言比較穩定的產品，包裝大，因此很多實驗室都會公用一個二抗。但如果二抗沒有選擇好的話，影響的可能就是一整個實驗室或者課題組了。艾美
Apoptotic cell death can be triggered by many different cellular stimuli, resulting in activation of apoptotic signaling pathways including caspases (
BRCA1 and BRCA2 were identified genetically as breast cancer susceptibility genes when a single copy of the gene is mutated and are involved in the ce
Nerve growth factor (NGF) is one of a family of neurotrophins that induce the survival and proliferation of neurons. In cell culture NGF induces the f
The differentiation of muscle cells is transcriptionally regulated, in part by the myocyte enhancer factor-2, MEF2. During myogenesis MEF2 binds to My
Nicotinic acetylcholine receptors are essential for neuromuscular signaling and are also expressed in non-neuronal tissues, where their function is le
Thrombin is an extracellular protease that is involved in the clotting of blood and inflammation through its action on platelets and endothelial cells
As with many cell-surface receptors, activation of the EGF receptor can result in receptor internalization through receptor-mediated endocytosis, dese
鑒于我國動物比較免疫學研究近期的系列重要進展，國際動物學期刊Developmental and Comparative Immunology雜志特邀中國科學院海洋研究所相建海研究員和中國農業大學趙要風教授作為客座主編，編輯出版了《中國比較免疫學研究進展》(Comparative Immu
The insulin resistance of type II diabetes appears to be caused in part by the presence of high levels of lipids in cells such as skeletal muscle wher
The IL-2 receptor is a key component of immune signaling and is required for the activation, proliferation, and survival of T cells. This receptor is
Lipopolysaccharide (LPS) from XX bacteria induces a wide range of inflammatory responses, including the response of alveolar macrophages to bacteria i
We also used this mutant (SMdC) as a host to generate two types of lacZ transcriptional reporter fusion strains to assay the promoter activi
Interleukin-12 (IL-12) promotes cell-mediated immunity by inducing Th1 cell differentiation and activation of both T cells and NK cells. Dendritic cel
Presenilin-1 (PS1) is associated with gamma secretase activity that cleaves amyloid precursor protein (APP) and is implicated in Alzheimer'